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Fluorescence-detection size-exclusion chromatography utilizing nanobody technology for expression screening of membrane proteins

GFP fusion-based fluorescence-detection size-exclusion chromatography (FSEC) has been widely employed for membrane protein expression screening. However, fused GFP itself may occasionally affect the expression and/or stability of the targeted membrane protein, leading to both false-positive and fals...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Jin, Fei, Shen, Cheng, Wang, Yao, Wang, Mengqi, Sun, Minxuan, Hattori, Motoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979870/
https://ncbi.nlm.nih.gov/pubmed/33742097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01891-y
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