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Epigenetic mechanisms in breast cancer therapy and resistance

The majority of breast cancers express the estrogen receptor (ERα) and agents targeting this pathway represent the main treatment modality. Endocrine therapy has proven successful in the treatment of hormone-responsive breast cancer since its early adoption in the 1940s as an ablative therapy. Unfor...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Garcia-Martinez, Liliana, Zhang, Yusheng, Nakata, Yuichiro, Chan, Ho Lam, Morey, Lluis
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979820/
https://ncbi.nlm.nih.gov/pubmed/33741974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22024-3
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