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Estrogen induces dynamic ERα and RING1B recruitment to control gene and enhancer activities in luminal breast cancer
RING1B, a core Polycomb repressive complex 1 subunit, is a histone H2A ubiquitin ligase essential for development. RING1B is overexpressed in patients with luminal breast cancer (BC) and recruited to actively transcribed genes and enhancers co-occupied by the estrogen receptor α (ERα). Whether ERα-i...
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| Gepubliceerd in: | Sci Adv |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Association for the Advancement of Science
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7274770/ https://ncbi.nlm.nih.gov/pubmed/32548262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz7249 |
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