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Molecular basis of V-ATPase inhibition by bafilomycin A1
Pharmacological inhibition of vacuolar-type H(+)-ATPase (V-ATPase) by its specific inhibitor can abrogate tumor metastasis, prevent autophagy, and reduce cellular signaling responses. Bafilomycin A1, a member of macrolide antibiotics and an autophagy inhibitor, serves as a specific and potent V-ATPa...
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| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7979754/ https://ncbi.nlm.nih.gov/pubmed/33741963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22111-5 |
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