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The Binding Site of the V-ATPase Inhibitor Apicularen Is in the Vicinity of Those for Bafilomycin and Archazolid

The investigation of V-ATPases as potential therapeutic drug targets and hence of their specific inhibitors is a promising approach in osteoporosis and cancer treatment because the occurrence of these diseases is interrelated to the function of the V-ATPase. Apicularen belongs to the novel inhibitor...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Osteresch, Christin, Bender, Tobias, Grond, Stephanie, von Zezschwitz, Paultheo, Kunze, Brigitte, Jansen, Rolf, Huss, Markus, Wieczorek, Helmut
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442520/
https://ncbi.nlm.nih.gov/pubmed/22815478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.372169
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