Archazolid A Binds to the Equatorial Region of the c-Ring of the Vacuolar H(+)-ATPase

The macrolactone archazolid is a novel, highly specific V-ATPase inhibitor with an IC(50) value in the low nanomolar range. The binding site of archazolid is presumed to overlap with the binding site of the established plecomacrolide V-ATPase inhibitors bafilomycin and concanamycin in subunit c of t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bockelmann, Svenja, Menche, Dirk, Rudolph, Sven, Bender, Tobias, Grond, Stephanie, von Zezschwitz, Paultheo, Muench, Stephen P., Wieczorek, Helmut, Huss, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992264/
https://ncbi.nlm.nih.gov/pubmed/20884613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.137539
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados