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A comprehensive influenza reporter virus panel for high-throughput deep profiling of neutralizing antibodies

Broadly neutralizing antibodies (bnAbs) have been developed as potential countermeasures for seasonal and pandemic influenza. Deep characterization of these bnAbs and polyclonal sera provides pivotal understanding for influenza immunity and informs effective vaccine design. However, conventional vir...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Creanga, Adrian, Gillespie, Rebecca A., Fisher, Brian E., Andrews, Sarah F., Lederhofer, Julia, Yap, Christina, Hatch, Liam, Stephens, Tyler, Tsybovsky, Yaroslav, Crank, Michelle C., Ledgerwood, Julie E., McDermott, Adrian B., Mascola, John R., Graham, Barney S., Kanekiyo, Masaru
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979723/
https://ncbi.nlm.nih.gov/pubmed/33741916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21954-2
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