Pharmacokinetics, Bioequivalence and Safety Evaluation of Two Ticagrelor Tablets Under Fasting and Fed Conditions in Healthy Chinese Subjects

PURPOSE: To evaluate the pharmacokinetics (PK), bioequivalence and safety profiles of test drug and reference drug of 90 mg ticagrelor tablets and their main active metabolite AR-C124910XX under fasting and fed conditions. METHODS: This was a randomized, open-label, single-dose, two-period, two-sequ...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Wang, Jin, Zhang, Huan, Wang, Rui, Cai, Yun
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2021
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979338/
https://ncbi.nlm.nih.gov/pubmed/33758499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S297918
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