Optimal anchoring of a foldamer inhibitor of ASF1 histone chaperone through backbone plasticity

Sequence-specific oligomers with predictable folding patterns, i.e., foldamers, provide new opportunities to mimic α-helical peptides and design inhibitors of protein-protein interactions. One major hurdle of this strategy is to retain the correct orientation of key side chains involved in protein s...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Mbianda, Johanne, Bakail, May, André, Christophe, Moal, Gwenaëlle, Perrin, Marie E., Pinna, Guillaume, Guerois, Raphaël, Becher, Francois, Legrand, Pierre, Traoré, Seydou, Douat, Céline, Guichard, Gilles, Ochsenbein, Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7978421/
https://ncbi.nlm.nih.gov/pubmed/33741589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd9153
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