Copy number loss in granzyme genes confers resistance to immune checkpoint inhibitor in nasopharyngeal carcinoma

BACKGROUND: Anti-programmed death (PD)-1 therapy has recently been used in recurrent or metastatic (R/M) nasopharyngeal carcinoma (NPC). The long-term survival and its biomarkers responding to anti-PD-1 treatment in patients with R/M NPC remain unclear. METHODS: Patients with R/M NPC were enrolled b...

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Udgivet i:J Immunother Cancer
Main Authors: Ma, Yuxiang, Chen, Xi, Wang, Ao, Zhao, Hongyun, Lin, Qingguang, Bao, Hua, Zhang, Yang, Hong, Shaodong, Tang, Wanxiangfu, Huang, Yan, Yang, Yunpeng, Wu, Xue, Shao, Yang, Fang, Wenfeng, Zhang, Li
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2021
Fag:
Immunotherapy Biomarkers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7978327/
https://ncbi.nlm.nih.gov/pubmed/33737344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-002014
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