The histone acetyltransferase HBO1 functions as a novel oncogenic gene in osteosarcoma

HBO1 (KAT7 or MYST2) is a histone acetyltransferase that acetylates H3 and H4 histones. Methods: HBO1 expression was tested in human OS tissues and cells. Genetic strategies, including shRNA, CRISPR/Cas9 and overexpression constructs, were applied to exogenously alter HBO1 expression in OS cells. Th...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Theranostics
Main Authors: Gao, Yan-yang, Ling, Zhuo-yan, Zhu, Yun-Rong, Shi, Ce, Wang, Yin, Zhang, Xiang-yang, Zhang, Zhi-qing, Jiang, Qin, Chen, Min-Bin, Yang, Shuofei, Cao, Cong
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2021
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7978299/
https://ncbi.nlm.nih.gov/pubmed/33754016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.55655
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