Pancreatic ductal deletion of S100A9 alleviates acute pancreatitis by targeting VNN1-mediated ROS release to inhibit NLRP3 activation

Recent studies have proven that the overall pathophysiology of pancreatitis involves not only the pancreatic acinar cells but also duct cells, however, pancreatic duct contribution in acinar cells homeostasis is poorly known and the molecular mechanisms leading to acinar insult and acute pancreatiti...

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Foilsithe in:Theranostics
Main Authors: Xiang, Hong, Guo, Fangyue, Tao, Xufeng, Zhou, Qi, Xia, Shilin, Deng, Dawei, Li, Lunxu, Shang, Dong
Formáid: Artigo
Teanga:Inglês
Foilsithe: Ivyspring International Publisher 2021
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7977474/
https://ncbi.nlm.nih.gov/pubmed/33754072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.54245
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