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Adipose-derived mesenchymal stem cells attenuate dialysis-induced peritoneal fibrosis by modulating macrophage polarization via interleukin-6

BACKGROUND: Life-long peritoneal dialysis (PD) as a renal replacement therapy is limited by peritoneal fibrosis. Previous studies showed immunomodulatory and antifibrotic effects of adipose-derived mesenchymal stem cells (ADSCs) on peritoneal fibrosis. However, the role of the peritoneal macrophage...

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Publicado en:Stem Cell Res Ther
Autores principales: Yang, Chih-Yu, Chang, Pu-Yuan, Chen, Jun-Yi, Wu, Bo-Sheng, Yang, An-Hang, Lee, Oscar Kuang-Sheng
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7977319/
https://ncbi.nlm.nih.gov/pubmed/33741073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02270-4
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