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Targeting Src attenuates peritoneal fibrosis and inhibits the epithelial to mesenchymal transition

Src has been reported to mediate tissue fibrosis in several organs, but its role in peritoneal fibrosis remains unknown. In this study, we evaluated the therapeutic effect of KX2-391, a highly selective inhibitor of Src, on the development of peritoneal fibrosis in a rat model. Daily intraperitoneal...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Wang, Jun, Wang, Li, Xu, Liuqing, Shi, Yingfeng, Liu, Feng, Qi, Hualin, Liu, Na, Zhuang, Shougang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663561/
https://ncbi.nlm.nih.gov/pubmed/29137389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20040
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