Targeting Src attenuates peritoneal fibrosis and inhibits the epithelial to mesenchymal transition

Src has been reported to mediate tissue fibrosis in several organs, but its role in peritoneal fibrosis remains unknown. In this study, we evaluated the therapeutic effect of KX2-391, a highly selective inhibitor of Src, on the development of peritoneal fibrosis in a rat model. Daily intraperitoneal...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Wang, Jun, Wang, Li, Xu, Liuqing, Shi, Yingfeng, Liu, Feng, Qi, Hualin, Liu, Na, Zhuang, Shougang
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663561/
https://ncbi.nlm.nih.gov/pubmed/29137389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20040
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