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Targeting Src attenuates peritoneal fibrosis and inhibits the epithelial to mesenchymal transition
Src has been reported to mediate tissue fibrosis in several organs, but its role in peritoneal fibrosis remains unknown. In this study, we evaluated the therapeutic effect of KX2-391, a highly selective inhibitor of Src, on the development of peritoneal fibrosis in a rat model. Daily intraperitoneal...
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| Publicado en: | Oncotarget |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5663561/ https://ncbi.nlm.nih.gov/pubmed/29137389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20040 |
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