Astrocyte-specific hypoxia-inducible factor 1 (HIF-1) does not disrupt the endothelial barrier during hypoxia in vitro

BACKGROUND: Astrocytes (AC) are essential for brain homeostasis. Much data suggests that AC support and protect the vascular endothelium, but increasing evidence indicates that during injury conditions they may lose their supportive role resulting in endothelial cell activation and BBB disturbance....

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Dades bibliogràfiques
Publicat a:Fluids Barriers CNS
Autors principals: Baumann, Julia, Tsao, Chih-Chieh, Huang, Sheng-Fu, Gassmann, Max, Ogunshola, Omolara O.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7977259/
https://ncbi.nlm.nih.gov/pubmed/33736658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-021-00247-2
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