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Third-line therapy for chronic myeloid leukemia: current status and future directions

Chronic myeloid leukemia (CML) is driven by the BCR-ABL1 fusion protein, formed by a translocation between chromosomes 9 and 22 that creates the Philadelphia chromosome. The BCR-ABL1 fusion protein is an optimal target for tyrosine kinase inhibitors (TKIs) that aim for the adenosine triphosphate (AT...

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Dades bibliogràfiques
Publicat a:J Hematol Oncol
Autors principals: Cortes, Jorge, Lang, Fabian
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7976694/
https://ncbi.nlm.nih.gov/pubmed/33736651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-021-01055-9
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