Use of Ultrasmall Core-Shell Fluorescent Silica Nanoparticles for Image-Guided Sentinel Lymph Node Biopsy in Head and Neck Melanoma: A Nonrandomized Clinical Trial

IMPORTANCE: Sentinel lymph node (SLN) mapping agents approved for current surgical practice lack sufficient brightness and target specificity for high-contrast, sensitive nodal visualization. OBJECTIVE: To evaluate whether an ultrasmall, molecularly targeted core-shell silica nanoparticle (Cornell p...

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Pubblicato in:JAMA Netw Open
Autori principali: Zanoni, Daniella Karassawa, Stambuk, Hilda E., Madajewski, Brian, Montero, Pablo H., Matsuura, Danielli, Busam, Klaus J., Ma, Kai, Turker, Melik Z., Sequeira, Sonia, Gonen, Mithat, Zanzonico, Pat, Wiesner, Ulrich, Bradbury, Michelle S., Patel, Snehal G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Medical Association 2021
Soggetti:
Original Investigation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7974643/
https://ncbi.nlm.nih.gov/pubmed/33734415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2021.1936
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