Use of Ultrasmall Core-Shell Fluorescent Silica Nanoparticles for Image-Guided Sentinel Lymph Node Biopsy in Head and Neck Melanoma: A Nonrandomized Clinical Trial

IMPORTANCE: Sentinel lymph node (SLN) mapping agents approved for current surgical practice lack sufficient brightness and target specificity for high-contrast, sensitive nodal visualization. OBJECTIVE: To evaluate whether an ultrasmall, molecularly targeted core-shell silica nanoparticle (Cornell p...

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Detalhes bibliográficos
Publicado no:JAMA Netw Open
Main Authors: Zanoni, Daniella Karassawa, Stambuk, Hilda E., Madajewski, Brian, Montero, Pablo H., Matsuura, Danielli, Busam, Klaus J., Ma, Kai, Turker, Melik Z., Sequeira, Sonia, Gonen, Mithat, Zanzonico, Pat, Wiesner, Ulrich, Bradbury, Michelle S., Patel, Snehal G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2021
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7974643/
https://ncbi.nlm.nih.gov/pubmed/33734415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2021.1936
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