20(s)-ginseonside-Rg3 modulation of AMPK/FoxO3 signaling to attenuate mitochondrial dysfunction in a dexamethasone-injured C2C12 myotube-based model of skeletal atrophy in vitro

Muscle atrophy, a side effect from administration of the anti-inflammatory medication dexamethasone (DEX), is preventable by concomitant administration of the major monomeric constituent of Panax ginseng C.A. Meyer, 20(S)-ginsenoside Rg3 (S-Rg3). Putative S-Rg3-associated prevention of DEX-induced m...

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Pubblicato in:Mol Med Rep
Autori principali: Wang, Manying, Jiang, Rui, Liu, Jianzeng, Xu, Xiaohao, Sun, Guang, Zhao, Daqing, Sun, Liwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2021
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7974265/
https://ncbi.nlm.nih.gov/pubmed/33649814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.11945
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