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Quercetin can reduce viral RNA level of O’nyong-nyong virus and resulting innate immune cytokine responses in cultured human synovial fibroblasts

O’nyong-nyong virus is an alphavirus closely related to chikungunya virus, causing arthralgia, rash and fever. Alphaviruses mainly target synovial fibroblasts and persists in the joints of patients, possibly leading to chronic arthritis. To date, no specific antiviral treatment is available for ONNV...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Septembre-Malaterre, Axelle, Bedoui, Yosra, Giry, Claude, Gasque, Philippe, Guiraud, Pascale, Sélambarom, Jimmy
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973764/
https://ncbi.nlm.nih.gov/pubmed/33737658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85840-z
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