4-methylumbelliferone-mediated polarization of M1 macrophages correlate with decreased hepatocellular carcinoma aggressiveness in mice

Hepatocellular carcinoma (HCC) arises in the setting of advanced liver fibrosis, a dynamic and complex inflammatory disease. The tumor microenvironment (TME) is a mixture of cellular components including cancer cells, cancer stem cells (CSCs), tumor-associated macrophages (TAM), and dendritic cells...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rodríguez, Marcelo M., Onorato, Agostina, Cantero, María José, Domínguez, Luciana, Bayo, Juan, Fiore, Esteban, García, Mariana, Atorrasagasti, Catalina, Canbay, Ali, Malvicini, Mariana, Mazzolini, Guillermo D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973733/
https://ncbi.nlm.nih.gov/pubmed/33737571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85491-0
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