Diverse metabolic response of cancer cells treated with a (213)Bi-anti-EGFR-immunoconjugate

Evaluation of treatment response is among the major challenges in modern oncology. We herein used a monoclonal antibody targeting the EGF receptor (EGFR) labelled with the alpha emitter (213)Bi ((213)Bi-anti-EGFR-MAb). EJ28Luc (bladder) and LN18 (glioma) cancer cells, both overexpressing EGFR, were...

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Udgivet i:Sci Rep
Main Authors: Feuerecker, Benedikt, Biechl, Philipp, Seidl, Christof, Bruchertseifer, Frank, Morgenstern, Alfred, Schwaiger, Markus, Eisenreich, Wolfgang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973706/
https://ncbi.nlm.nih.gov/pubmed/33737524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84421-4
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