Gabapentin Therapy for Amyotrophic Lateral Sclerosis: Lack of Improvement in Neuronal Integrity Shown by MR Spectroscopy

BACKGROUND AND PURPOSE: Proton MR spectroscopy has revealed impaired neuronal integrity in the motor cortex of patients with amyotrophic lateral sclerosis (ALS). We hypothesized that the N-acetylaspartate (NAA)-creatine (Cr) ratios in the motor cortex and adjacent brain could reflect the therapeutic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:AJNR Am J Neuroradiol
Prif Awduron: Kalra, Sanjay, Cashman, Neil R., Caramanos, Zografos, Genge, Angela, Arnold, Douglas L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Neuroradiology 2003
Pynciau:
Brain
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973590/
https://ncbi.nlm.nih.gov/pubmed/12637300
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