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Gabapentin Therapy for Amyotrophic Lateral Sclerosis: Lack of Improvement in Neuronal Integrity Shown by MR Spectroscopy

BACKGROUND AND PURPOSE: Proton MR spectroscopy has revealed impaired neuronal integrity in the motor cortex of patients with amyotrophic lateral sclerosis (ALS). We hypothesized that the N-acetylaspartate (NAA)-creatine (Cr) ratios in the motor cortex and adjacent brain could reflect the therapeutic...

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Detalhes bibliográficos
Publicado no:AJNR Am J Neuroradiol
Main Authors: Kalra, Sanjay, Cashman, Neil R., Caramanos, Zografos, Genge, Angela, Arnold, Douglas L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Neuroradiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973590/
https://ncbi.nlm.nih.gov/pubmed/12637300
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