METTL3 Regulates Ossification of the Posterior Longitudinal Ligament via the lncRNA XIST/miR-302a-3p/USP8 Axis

The prevalence of ossification of the posterior longitudinal ligament (OPLL) is increasing, and currently there is no effective medical treatment for OPLL. Methyltransferase like 3 (METTL3), one of the components of the N(6)-methyladenosine (m(6)A) methyltransferase complex, regulates gene expressio...

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Bibliographic Details
Published in:Front Cell Dev Biol
Main Authors: Yuan, Xiaoqiu, Shi, Lei, Guo, Yongfei, Sun, Jingchuan, Miao, Jinhao, Shi, Jiangang, Chen, Yu
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Cell and Developmental Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973222/
https://ncbi.nlm.nih.gov/pubmed/33748113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.629895
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