Formulation development of itraconazole PEGylated nano-lipid carriers for pulmonary aspergillosis using hot-melt extrusion technology

Pulmonary delivery is a promising alternative for the oral treatment of pulmonary aspergillosis. This study aimed to develop continuous and scalable itraconazole PEGylated nano-lipid carriers (ITZ-PEG-NLC) for inhalation delivery. The feasibility of preparing NLCs utilizing hot-melt extrusion (HME)...

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Detalles Bibliográficos
Publicado en:Int J Pharm X
Main Authors: Shadambikar, Gauri, Marathe, Sushrut, Ji, Nan, Almutairi, Mashan, Bandari, Suresh, Zhang, Feng, Chougule, Mahavir, Repka, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2021
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973123/
https://ncbi.nlm.nih.gov/pubmed/33748741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpx.2021.100074
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