Abrogating mitochondrial ROS in neurons or astrocytes reveals cell-specific impact on mouse behaviour

Cells naturally produce mitochondrial reactive oxygen species (mROS), but the in vivo pathophysiological significance has long remained controversial. Within the brain, astrocyte-derived mROS physiologically regulate behaviour and are produced at one order of magnitude faster than in neurons. Howeve...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Vicente-Gutierrez, Carlos, Bonora, Nicolo, Jimenez-Blasco, Daniel, Lopez-Fabuel, Irene, Bates, Georgina, Murphy, Michael P., Almeida, Angeles, Bolaños, Juan P.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7972977/
https://ncbi.nlm.nih.gov/pubmed/33711713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.101917
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