Mitochondrial ROS Produced via Reverse Electron Transport Extend Animal Lifespan

Increased production of reactive oxygen species (ROS) has long been considered a cause of aging. However, recent studies have implicated ROS as essential secondary messengers. Here we show that the site of ROS production significantly contributes to their apparent dual nature. We report that ROS inc...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Scialò, Filippo, Sriram, Ashwin, Fernández-Ayala, Daniel, Gubina, Nina, Lõhmus, Madis, Nelson, Glyn, Logan, Angela, Cooper, Helen M., Navas, Plácido, Enríquez, Jose Antonio, Murphy, Michael P., Sanz, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
Assuntos:
Short Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835580/
https://ncbi.nlm.nih.gov/pubmed/27076081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.03.009
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