Mitochondrial complex I derived ROS regulate stress adaptation in Drosophila melanogaster

Reactive Oxygen Species (ROS) are essential cellular messengers required for cellular homeostasis and regulate the lifespan of several animal species. The main site of ROS production is the mitochondrion, and within it, respiratory complex I (CI) is the main ROS generator. ROS produced by CI trigger...

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Hauptverfasser: Filippo Scialò, Ashwin Sriram, Rhoda Stefanatos, Ruth V. Spriggs, Samantha H.Y. Loh, L. Miguel Martins, Alberto Sanz
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020-05-01
Schriftenreihe:Redox Biology
Schlagworte:
Heat stress
Reverse electron transport
Complex I
Reactive oxygen species
Alternative oxidase
AOX
Online Zugang:http://www.sciencedirect.com/science/article/pii/S2213231719314600
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