Circulatory Loop Design and Components Introduce Artifacts Impacting In-Vitro Evaluation of Ventricular Assist Device Thrombogenicity: A Call for Caution

Mechanical circulatory support (MCS) devices continue to be hampered by thrombotic adverse events, a consequence of device-imparted supraphysiologic shear stresses, leading to shear-mediated platelet activation (SMPA). In advancing MCS devices from design to clinical use, in-vitro circulatory loops...

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Vydáno v:Artif Organs
Hlavní autoři: Li, Mengtang, Walk, Ryan, Roka-Moiia, Yana, Sheriff, Jawaad, Bluestein, Danny, Barth, Eric J., Slepian, Marvin J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7972931/
https://ncbi.nlm.nih.gov/pubmed/31876310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aor.13626
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