Low-dose hydralazine during gestation reduces renal fibrosis in rodent offspring exposed to maternal high fat diet

BACKGROUND: Maternal high fat diet (HFD) promotes chronic kidney disease (CKD) in offspring. This is in accordance with the theory of fetal programming, which suggests adverse conditions occurring in utero predispose offspring to chronic conditions later in life. DNA methylation has been proposed as...

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Publicat a:PLoS One
Autors principals: Larkin, Benjamin P., Saad, Sonia, Glastras, Sarah J., Nguyen, Long T., Hou, Miao, Chen, Hui, Wang, Rosy, Pollock, Carol A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7971884/
https://ncbi.nlm.nih.gov/pubmed/33735324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0248854
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