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SIRT1 overexpression attenuates offspring metabolic and liver disorders as a result of maternal high‐fat feeding
KEY POINTS: Maternal high‐fat diet (MHF) consumption led to metabolic and liver disorders in male offspring, which are associated with reduced sirtuin (SIRT)1 expression and activity in the offspring liver. SIRT1 overexpression in MHF offspring reduced their body weight and adiposity and normalized...
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| Опубликовано в: : | J Physiol |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6332732/ https://ncbi.nlm.nih.gov/pubmed/30381838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276957 |
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