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A multiscale model via single-cell transcriptomics reveals robust patterning mechanisms during early mammalian embryo development
During early mammalian embryo development, a small number of cells make robust fate decisions at particular spatial locations in a tight time window to form inner cell mass (ICM), and later epiblast (Epi) and primitive endoderm (PE). While recent single-cell transcriptomics data allows scrutinizatio...
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| 發表在: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7971879/ https://ncbi.nlm.nih.gov/pubmed/33684098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008571 |
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