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Inferring spatial and signaling relationships between cells from single cell transcriptomic data

Single-cell RNA sequencing (scRNA-seq) provides details for individual cells; however, crucial spatial information is often lost. We present SpaOTsc, a method relying on structured optimal transport to recover spatial properties of scRNA-seq data by utilizing spatial measurements of a relatively sma...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Cang, Zixuan, Nie, Qing
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190659/
https://ncbi.nlm.nih.gov/pubmed/32350282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15968-5
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