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A computational study of co-inhibitory immune complex assembly at the interface between T cells and antigen presenting cells

The activation and differentiation of T-cells are mainly directly by their co-regulatory receptors. T lymphocyte-associated protein-4 (CTLA-4) and programed cell death-1 (PD-1) are two of the most important co-regulatory receptors. Binding of PD-1 and CTLA-4 with their corresponding ligands programe...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Su, Zhaoqian, Dhusia, Kalyani, Wu, Yinghao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7971848/
https://ncbi.nlm.nih.gov/pubmed/33684103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008825
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