Adenosine A(2A) receptor agonist polydeoxyribonucleotide ameliorates short-term memory impairment by suppressing cerebral ischemia-induced inflammation via MAPK pathway

Cerebral ischemia causes tissue death owing to occlusion of the cerebral blood vessels, and cerebral ischemia activates mitogen-activated protein kinase (MAPK) and induces secretion of pro-inflammatory cytokines. Adenosine A(2A) receptor agonist, polydeoxyribonucleotide (PDRN), suppresses the secret...

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Publicado en:PLoS One
Main Authors: Ko, Il-Gyu, Jin, Jun-Jang, Hwang, Lakkyong, Kim, Sang-Hoon, Kim, Chang-Ju, Jeon, Jung Won, Chung, Jun-Young, Han, Jin Hee
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2021
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7971468/
https://ncbi.nlm.nih.gov/pubmed/33735236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0248689
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