Polydeoxyribonucleotide Exerts Protective Effect Against CCl(4)-Induced Acute Liver Injury through Inactivation of NF-κB/MAPK Signaling Pathway in Mice

Acute liver injury (ALI) causes life-threatening clinical problem, and its underlying etiology includes inflammation and apoptosis. An adenosine A(2A) receptor agonist, polydeoxyribonucleotide (PDRN), exhibits anti-inflammatory and anti-apoptotic effects by inhibiting the secretion of pro-inflammato...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ko, Il-Gyu, Jin, Jun-Jang, Hwang, Lakkyong, Kim, Sang-Hoon, Kim, Chang-Ju, Han, Jin Hee, Lee, Seunghwan, Kim, Ha Il, Shin, Hyun Phil, Jeon, Jung Won
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660684/
https://ncbi.nlm.nih.gov/pubmed/33114315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21217894
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