ACKR4 restrains antitumor immunity by regulating CCL21

Current immunotherapies involving CD8(+) T cell responses show remarkable promise, but their efficacy in many solid tumors is limited, in part due to the low frequency of tumor-specific T cells in the tumor microenvironment (TME). Here, we identified a role for host atypical chemokine receptor 4 (AC...

詳細記述

保存先:
書誌詳細
出版年:J Exp Med
主要な著者: Whyte, Carly E., Osman, Maleika, Kara, Ervin E., Abbott, Caitlin, Foeng, Jade, McKenzie, Duncan R., Fenix, Kevin A., Harata-Lee, Yuka, Foyle, Kerrie L., Boyle, Sarah T., Kochetkova, Marina, Aguilera, Amelia Roman, Hou, Jiajie, Li, Xian-Yang, Armstrong, Mark A., Pederson, Stephen M., Comerford, Iain, Smyth, Mark J., McColl, Shaun R.
フォーマット: Artigo
言語:Inglês
出版事項: Rockefeller University Press 2020
主題:
Brief Definitive Report
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7971131/
https://ncbi.nlm.nih.gov/pubmed/32289156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190634
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