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Gene co-expression network analysis in human spinal cord highlights mechanisms underlying amyotrophic lateral sclerosis susceptibility

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease defined by motor neuron (MN) loss. Multiple genetic risk factors have been identified, implicating RNA and protein metabolism and intracellular transport, among other biological mechanisms. To achieve a systems-level understanding of...

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Publicado en:Sci Rep
Main Authors: Wang, Jerry C., Ramaswami, Gokul, Geschwind, Daniel H.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7970949/
https://ncbi.nlm.nih.gov/pubmed/33707641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85061-4
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