Longitudinal evaluation of cerebral and spinal cord damage in Amyotrophic Lateral Sclerosis

OBJECTIVE: To evaluate MRI-based parameters as biomarkers of Amyotrophic Lateral Sclerosis (ALS) progression. METHODS: Twenty-seven patients and 27 controls performed two clinical and MRI acquisitions 8 months apart. ALSFRS-R scale was used to quantify disease severity at both time points. Multimoda...

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Bibliographic Details
Published in:Neuroimage Clin
Main Authors: de Albuquerque, Milena, Branco, Lucas Melo T, Rezende, Thiago Junqueira R., de Andrade, Helen Maia Tavares, Nucci, Anamarli, França Jr, Marcondes Cavalcante
Format: Artigo
Language:Inglês
Published: Elsevier 2017
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Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294732/
https://ncbi.nlm.nih.gov/pubmed/28203530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2017.01.024
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