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Variability in mRNA translation: a random matrix theory approach

The rate of mRNA translation depends on the initiation, elongation, and termination rates of ribosomes along the mRNA. These rates depend on many “local” factors like the abundance of free ribosomes and tRNA molecules in the vicinity of the mRNA molecule. All these factors are stochastic and their e...

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Publicado en:Sci Rep
Autores principales: Margaliot, Michael, Huleihel, Wasim, Tuller, Tamir
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7970873/
https://ncbi.nlm.nih.gov/pubmed/33674667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84738-0
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