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Rational Design of Multistage Drug Delivery Vehicles for Pulmonary RNA Interference Therapy

Small interfering RNA (siRNA) therapy has significant potential for the treatment of myriad diseases, including cancer. While intravenous routes of delivery have been found to be effective for efficient targeting to the liver, achieving high accumulations selectively in other organs, including lung...

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Detalhes bibliográficos
Publicado no:Int J Pharm
Main Authors: Silva, A. Sofia, Shopsowitz, Kevin E., Correa, Santiago, Morton, Stephen W., Dreaden, Erik C., Casimiro, Teresa, Aguiar-Ricardo, Ana, Hammond, Paula T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7970503/
https://ncbi.nlm.nih.gov/pubmed/33122113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2020.119989
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