TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression

As a key risk factor for lung cancer, tobacco smoke (TS) influences several cellular processes, including epithelial-mesenchymal transition (EMT). TAp63α is a crucial transcription factor involved in tumor progression. The present study was designed to investigate the potential role and underlying m...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Xie, Chunfeng, Zhu, Jianyun, Yang, Xue, Huang, Cong, Zhou, Liping, Meng, Zili, Li, Xiaoting, Zhong, Caiyun
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7970191/
https://ncbi.nlm.nih.gov/pubmed/33748140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.645402
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