The Functional Classification of ORF8 in SARS-CoV-2 Replication, Immune Evasion, and Viral Pathogenesis Inferred through Phylogenetic Profiling

ORF8 is a highly variable genomic region of SARS-CoV-2. Although non-essential and the precise functions are unknown, it has been suggested that this protein assists in SARS-CoV-2 replication in the early secretory pathway and in immune evasion. We utilized the binding partners of SARS-CoV-2 protein...

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Bibliographic Details
Published in:Evol Bioinform Online
Main Authors: Fahmi, Muhamad, Kitagawa, Hiromu, Yasui, Gen, Kubota, Yukihiko, Ito, Masahiro
Format: Artigo
Language:Inglês
Published: SAGE Publications 2021
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7970180/
https://ncbi.nlm.nih.gov/pubmed/33795929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/11769343211003079
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