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In Silico Study of Rett Syndrome Treatment-Related Genes, MECP2, CDKL5, and FOXG1, by Evolutionary Classification and Disordered Region Assessment

Rett syndrome (RTT), a neurodevelopmental disorder, is mainly caused by mutations in methyl CpG-binding protein 2 (MECP2), which has multiple functions such as binding to methylated DNA or interacting with a transcriptional co-repressor complex. It has been established that alterations in cyclin-dep...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Fahmi, Muhamad, Yasui, Gen, Seki, Kaito, Katayama, Syouichi, Kaneko-Kawano, Takako, Inazu, Tetsuya, Kubota, Yukihiko, Ito, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6888432/
https://ncbi.nlm.nih.gov/pubmed/31717404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20225593
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