Effect of memantine, an anti-Alzheimer’s drug, on rodent microglial cells in vitro

The pathophysiology of Alzheimer’s disease (AD) is related to neuroinflammatory responses mediated by microglia. Memantine, an antagonist of N-methyl-d-aspartate (NMDA) receptors used as an anti-Alzheimer’s drug, protects from neuronal death accompanied by suppression of proliferation and activation...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Murakawa-Hirachi, Toru, Mizoguchi, Yoshito, Ohgidani, Masahiro, Haraguchi, Yoshinori, Monji, Akira
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969939/
https://ncbi.nlm.nih.gov/pubmed/33731780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85625-4
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