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Complement Activation in the Central Nervous System: A Biophysical Model for Immune Dysregulation in the Disease State

Complement, a feature of the innate immune system that targets pathogens for phagocytic clearance and promotes inflammation, is tightly regulated to prevent damage to host tissue. This regulation is paramount in the central nervous system (CNS) since complement proteins degrade neuronal synapses dur...

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Bibliografske podrobnosti
izdano v:Front Mol Neurosci
Main Authors: Peoples, Nicholas, Strang, Candace
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969890/
https://ncbi.nlm.nih.gov/pubmed/33746710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2021.620090
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