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Complement Activation in the Central Nervous System: A Biophysical Model for Immune Dysregulation in the Disease State

Complement, a feature of the innate immune system that targets pathogens for phagocytic clearance and promotes inflammation, is tightly regulated to prevent damage to host tissue. This regulation is paramount in the central nervous system (CNS) since complement proteins degrade neuronal synapses dur...

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Podrobná bibliografie
Vydáno v:Front Mol Neurosci
Hlavní autoři: Peoples, Nicholas, Strang, Candace
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969890/
https://ncbi.nlm.nih.gov/pubmed/33746710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2021.620090
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