Colonization of distant organs by tumor cells generating circulating homotypic clusters adaptive to fluid shear stress

Once disseminated tumor cells (DTCs) arrive at a metastatic organ, they remain there, latent, and become seeds of metastasis. However, the clonal composition of DTCs in a latent state remains unclear. Here, we applied high-resolution DNA barcode tracking to a mouse model that recapitulated the metas...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Maeshiro, Manabu, Shinriki, Satoru, Liu, Rin, Nakachi, Yutaka, Komohara, Yoshihiro, Fujiwara, Yukio, Ohtsubo, Kazuaki, Yoshida, Ryoji, Iwamoto, Kazuya, Nakayama, Hideki, Matsui, Hirotaka
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969766/
https://ncbi.nlm.nih.gov/pubmed/33731803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85743-z
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