NOD1 Agonist Protects Against Lipopolysaccharide and D-Galactosamine-Induced Fatal Hepatitis Through the Upregulation of A20 Expression in Hepatocytes

Increasing evidence suggests that NODs are involved in liver diseases; however, the underlying mechanisms remain obscure. In the present study, we analyzed the effect of NOD1 agonist pretreatment on acute liver failure induced by lipopolysaccharide (LPS) in D-galactosamine (D-GalN)-sensitized mice....

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Jia, Fang, Deng, Fuxue, Xu, Pan, Li, Shiying, Wang, Xuefu, Hu, Peng, Ren, Hong, Tong, Shiwen, Yin, Wenwei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969647/
https://ncbi.nlm.nih.gov/pubmed/33746949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.603192
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